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Structure paper

TitleCryo-EM structures of human monkeypox viral replication complexes with and without DNA duplex.
Journal, issue, pagesCell Res, Vol. 33, Issue 6, Page 479-482, Year 2023
Publish dateMar 27, 2023
AuthorsYunxia Xu / Yaqi Wu / Yuanyuan Zhang / Ruixin Fan / Yaxue Yang / Danyang Li / Shimin Zhu / Biao Yang / Zhengyu Zhang / Changjiang Dong /
External linksCell Res / PubMed:36973539 / PubMed Central
MethodsEM (single particle)
Resolution2.76 - 3.05 Å
Structure data

EMDB-34684, PDB-8hdz:
Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in an apo form
Method: EM (single particle) / Resolution: 3.05 Å

EMDB-34927, PDB-8hoy:
Cryo-EM structure of monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex without DNA at 2.76 angostram
Method: EM (single particle) / Resolution: 2.76 Å

EMDB-34929, PDB-8hpa:
Monkeypox virus DNA replication holoenzyme F8, A22 and E4 complex in a DNA binding form
Method: EM (single particle) / Resolution: 3.01 Å

Source
  • monkeypox virus
  • dna molecule (others)
KeywordsVIRAL PROTEIN / DNA replication machinery / F8 / A22 / E4 / DNA polymerase / B-family DNA polymerase / uracil-DNA glycosylase / MPXV / orthopoxvirus / poxviridae / DNA processivity factor / Monkeypox virus / DNA replication holoenzyme / F8-A22-E4 complex

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