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TitleMolecular determinants of cross-strain influenza A virus recognition by alpha beta T cell receptors.
Journal, issue, pagesSci Immunol, Vol. 10, Page eadn3805-eadn3805, Year 2025
Publish dateSep 27, 2022 (structure data deposition date)
AuthorsQuinones-Parra, S.M. / Gras, S. / Nguyen, T.H.O. / Farenc, C. / Szeto, C. / Rowntree, L.C. / Chaurasia, P. / Sant, S. / Boon, A.C.M. / Jayasinghe, D. ...Quinones-Parra, S.M. / Gras, S. / Nguyen, T.H.O. / Farenc, C. / Szeto, C. / Rowntree, L.C. / Chaurasia, P. / Sant, S. / Boon, A.C.M. / Jayasinghe, D. / Rimmelzwaan, G.F. / Petersen, J. / Doherty, P.C. / Uldrich, A.P. / Littler, D.R. / Rossjohn, J. / Kedzierska, K.
External linksSci Immunol / PubMed:39919196
MethodsX-ray diffraction
Resolution1.80482421415 - 2.6500177696 Å
Structure data

PDB-8emf:
Crystal structure of a HLA-B*35:01-NP6 epitope from 1977 H1N1 influenza strain
Method: X-RAY DIFFRACTION / Resolution: 1.80482421415 Å

PDB-8v4z:
Crystal structure of a HLA-B*35:01-NP7 with D1 TCR
Method: X-RAY DIFFRACTION / Resolution: 2.40000208775 Å

PDB-8v50:
Crystal structure of a HLA-B*35:01-NP6 with D1 TCR
Method: X-RAY DIFFRACTION / Resolution: 2.6500177696 Å

PDB-8v51:
Crystal structure of a HLA-B*35:01-NP10 with D1 TCR
Method: X-RAY DIFFRACTION / Resolution: 2.10000032944 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-PO4:
PHOSPHATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-NA:
Unknown entry

Source
  • homo sapiens (human)
  • influenza a virus (strain a/1977/h1n1)
  • influenza a virus
KeywordsIMMUNE SYSTEM / HLA B*3501 / NP418 epitope / T cell immunity / glycoprotein / host-virus interaction / immune response

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