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Structure paper

TitleSelective posttranslational inhibition of Ca V beta 1 -associated voltage-dependent calcium channels with a functionalized nanobody.
Journal, issue, pagesNat Commun, Vol. 13, Page 7556-7556, Year 2022
Publish dateJun 13, 2022 (structure data deposition date)
AuthorsMorgenstern, T.J. / Nirwan, N. / Hernandez-Ochoa, E.O. / Bibollet, H. / Choudhury, P. / Laloudakis, Y.D. / Ben Johny, M. / Bannister, R.A. / Schneider, M.F. / Minor Jr., D.L. / Colecraft, H.M.
External linksNat Commun / PubMed:36494348
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-8dam:
nbF3:nbE8:CaV beta subunit 1b complex
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-8e0e:
nbF3:CaV beta subunit 2a complex
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-CA:
Unknown entry

ChemComp-MG:
Unknown entry

Source
  • mus musculus (house mouse)
  • lama glama (llama)
  • rattus norvegicus (Norway rat)
KeywordsTRANSPORT PROTEIN/IMMUNE SYSTEM / nanobody-CACNB1b complex / TRANSPORT PROTEIN / TRANSPORT PROTEIN-IMMUNE SYSTEM complex / nanobody-CACNB2a complex / CYTOSOLIC PROTEIN

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