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TitleStructure and Dynamics of the Penicillin-Binding Protein 3 from Staphylococcus Epidermidis Native and in Complex with Cefotaxime and Vaborbactam
Journal, issue, pagesInt J Appl Biol Pharm, Year 2023
Publish dateJan 6, 2023 (structure data deposition date)
AuthorsSchwinzer, M. / Brognaro, H. / Rohde, H. / Betzel, C.
External linksInt J Appl Biol Pharm / Search PubMed
MethodsX-ray diffraction
Resolution2.3 - 2.51 Å
Structure data

PDB-8c5b:
Crystal Structure of Penicillin-binding Protein 3 (PBP3) from Staphylococcus Epidermidis
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-8c5o:
Crystal Structure of Penicillin-binding Protein 3 (PBP3) from Staphylococcus Epidermidis in complex with Vaborbactam
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-8c5w:
Crystal Structure of Penicillin-binding Protein 3 (PBP3) from Staphylococcus Epidermidis in complex with Cefotaxime
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

Chemicals

ChemComp-4D6:
Vaborbactam / antibiotic, inhibitor*YM

ChemComp-HOH:
WATER

ChemComp-CEF:
CEFOTAXIME, C3' cleaved, open, bound form / antibiotic*YM

Source
  • staphylococcus epidermidis (strain atcc 35984 / rp62a) (bacteria)
KeywordsPENICILLIN-BINDING PROTEIN

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