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-Structure paper
Title | Engineering of a Reductive Aminase to Enable the Synthesis of a Key Intermediate to a CDK 2/4/6 Inhibitor |
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Journal, issue, pages | Acs Catalysis, Vol. 13, Page 10065-10075, Year 2023 |
Publish date | Nov 3, 2022 (structure data deposition date) |
![]() | Steflik, J. / Gilio, A. / Burns, M. / Grogan, G. / Kumar, R. / Lewis, R. / Martinez, C. |
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Methods | X-ray diffraction |
Resolution | 2.7 - 2.72 Å |
Structure data | ![]() PDB-8bj5: ![]() PDB-8bk1: |
Chemicals | ![]() ChemComp-NAP: ![]() ChemComp-HOH: ![]() ChemComp-SO4: |
Source |
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![]() | OXIDOREDUCTASE / Amine / Imine NADPH / biocatalyst |