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TitlePeptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae.
Journal, issue, pagesSci Adv, Vol. 9, Page eadg3683-eadg3683, Year 2023
Publish dateJan 12, 2022 (structure data deposition date)
AuthorsSchuster, M. / Brabet, E. / Oi, K.K. / Desjonqueres, N. / Moehle, K. / Le Poupon, K. / Hell, S. / Gable, S. / Rithie, V. / Dillinger, S. ...Schuster, M. / Brabet, E. / Oi, K.K. / Desjonqueres, N. / Moehle, K. / Le Poupon, K. / Hell, S. / Gable, S. / Rithie, V. / Dillinger, S. / Zbinden, P. / Luther, A. / Li, C. / Stiegeler, S. / D'Arco, C. / Locher, H. / Remus, T. / DiMaio, S. / Motta, P. / Wach, A. / Jung, F. / Upert, G. / Obrecht, D. / Benghezal, M. / Zerbe, O.
External linksSci Adv / PubMed:37224246
MethodsNMR (solution)
Structure data

PDB-7qs6:
Solution structure of thanatin-like derivative 7 in complex with E.coli LptA
Method: SOLUTION NMR

PDB-7zax:
Solution structure of thanatin-like derivative 7 in complex with K. pneumoniae LptA
Method: SOLUTION NMR

PDB-7zed:
Solution structure of thanatin-like derivative 7 in complex with E.coli LptA mutant Q62L
Method: SOLUTION NMR

PDB-8bss:
Solution Structure of thanatin-like derivative 5 in complex with E. coli LptA mutant Q62L
Method: SOLUTION NMR

Source
  • escherichia coli k-12 (bacteria)
  • podisus maculiventris (spined soldier bug)
  • klebsiella pneumoniae (bacteria)
KeywordsANTIBIOTIC / STRUCTURE FROM CYANA 3.98.11 / STRUCTURE FROM CYANA 3.98.13

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