Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Fragment Ligands of the m 6 A-RNA Reader YTHDF2.
Journal, issue, pages	Acs Med. Chem. Lett., Vol. 13, Page 1500-1509, Year 2022
Publish date	Feb 10, 2022 (structure data deposition date)
Authors	Nai, F. / Nachawati, R. / Zalesak, F. / Wang, X. / Li, Y. / Caflisch, A.
External links	Acs Med. Chem. Lett. / PubMed:36110386
Methods	X-ray diffraction
Resolution	1.7 - 2.01 Å
Structure data	PDB-7r5f: Crystal structure of YTHDF2 with compound YLI_DF_012 Method: X-RAY DIFFRACTION / Resolution: 2 Å PDB-7r5l: Crystal structure of YTHDF2 with compound YLI_DC1_015 Method: X-RAY DIFFRACTION / Resolution: 1.7 Å PDB-7r5w: Crystal structure of YTHDF2 with compound YLI_DF_029 Method: X-RAY DIFFRACTION / Resolution: 1.75 Å PDB-7ywb: Crystal structure of YTHDF2 in complex with N6-Methyladenine Method: X-RAY DIFFRACTION / Resolution: 1.92 Å PDB-7yx6: Crystal structure of YTHDF2 with compound YLI_DF_027 Method: X-RAY DIFFRACTION / Resolution: 1.8 Å PDB-7yxe: Crystal structure of YTHDF2 with compound ZA_143 Method: X-RAY DIFFRACTION / Resolution: 1.85 Å PDB-7z26: Crystal structure of YTHDF2 YTH domain in complex with m6A RNA Method: X-RAY DIFFRACTION / Resolution: 1.9 Å PDB-7z4u: Crystal structure of YTHDF2 with compound YLI_DF_028 Method: X-RAY DIFFRACTION / Resolution: 1.83 Å PDB-7z54: Crystal structure of YTHDF2 with compound YLI_DC1_006 Method: X-RAY DIFFRACTION / Resolution: 1.82 Å PDB-7z5m: Crystal structure of YTHDF2 with compound YLI_DC1_008 Method: X-RAY DIFFRACTION / Resolution: 1.7 Å PDB-7z7b: Crystal structure of YTHDF2 with compound YLI_DC1_003 Method: X-RAY DIFFRACTION / Resolution: 1.8 Å PDB-7z7f: Crystal structure of YTHDF2 with compound YLI_DC1_005 Method: X-RAY DIFFRACTION / Resolution: 1.95 Å PDB-7z8p: Crystal structure of YTHDF2 with compound ZA_166 Method: X-RAY DIFFRACTION / Resolution: 1.97 Å PDB-7z8w: Crystal structure of YTHDF2 with compound YLI_DC1_018 Method: X-RAY DIFFRACTION / Resolution: 1.9 Å PDB-7z8x: Crystal structure of YTHDF2 with compound YLI_DC1_017 Method: X-RAY DIFFRACTION / Resolution: 1.96 Å PDB-7z92: Crystal structure of YTHDF2 with compound YLI_DF_024 Method: X-RAY DIFFRACTION / Resolution: 1.91 Å PDB-7z93: Crystal structure of YTHDF2 with compound YLI_DF_022 Method: X-RAY DIFFRACTION / Resolution: 1.97 Å PDB-7zg4: Crystal structure of YTHDF2 with compound YLI_DF_042 Method: X-RAY DIFFRACTION / Resolution: 2.01 Å
Chemicals	ChemComp-SO4: SULFATE ION ChemComp-CL: Unknown entry ChemComp-I3V: 5-azanyl-6-methyl-1~{H}-pyrimidine-2,4-dione ChemComp-HOH: WATER ChemComp-I4S: 3,6-dimethyl-2~{H}-1,2,4-triazin-5-one ChemComp-I5Z: 6-cyclopropyl-1H-pyrimidine-2,4-dione ChemComp-GOL: GLYCEROL ChemComp-N6M: N-METHYL-9H-PURIN-6-AMINE ChemComp-I6R: 6-ethyl-1H-pyrimidine-2,4-dione ChemComp-I82: ~{N}-methyl-3-phenyl-2~{H}-pyrazolo[4,3-d]pyrimidin-7-amine ChemComp-NA: Unknown entry ChemComp-FIQ: 6-cyclopropyl-3-methyl-1H-pyrimidine-2,4-dione ChemComp-OYT: 9-cyclopropyl-~{N}-methyl-purin-6-amine ChemComp-5ZK: ~{N},3-dimethyl-1~{H}-pyrazolo[4,3-d]pyrimidin-7-amine ChemComp-OYK: ~{N},9-dimethylpurin-6-amine ChemComp-IF3: ~{N}2,~{N}6,9-trimethylpurine-2,6-diamine ChemComp-IFZ: 3-bromanyl-~{N}-methyl-2~{H}-pyrazolo[4,3-d]pyrimidin-7-amine ChemComp-IHR: ~{N}-cyclopropyl-3-methyl-2~{H}-pyrazolo[4,3-d]pyrimidin-7-amine ChemComp-IGX: 6-methoxy-1H-pyrimidine-2,4-dione ChemComp-IGT: 5-azanyl-3,6-dimethyl-1H-pyrimidine-2,4-dione ChemComp-IHF: 5-azanyl-6-ethyl-1H-pyrimidine-2,4-dione ChemComp-IQL: N-methylpyrimidine-2-carboximidamide
Source	homo sapiens (human)
Keywords	RNA BINDING PROTEIN / epitranscriptomic reader / m6A reader / Epitranscriptomic reader m6A reader