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TitleTargeting NOX2 via p47/phox-p22/phox Inhibition with Novel Triproline Mimetics
Journal, issue, pagesAcs Med. Chem. Lett., Vol. 13, Page 949-954, Year 2022
Publish dateFeb 16, 2022 (structure data deposition date)
AuthorsGarsi, J.B. / Komjati, B. / Cullia, G. / Fejes, I. / Sipos, M. / Sipos, Z. / Fordos, E. / Markacz, P. / Balazs, B. / Lancelot, N. ...Garsi, J.B. / Komjati, B. / Cullia, G. / Fejes, I. / Sipos, M. / Sipos, Z. / Fordos, E. / Markacz, P. / Balazs, B. / Lancelot, N. / Berger, S. / Raimbaud, E. / Brown, D. / Vuillard, L.M. / Haberkorn, L. / Cukier, C. / Szlavik, Z. / Hanessian, S.
External linksAcs Med. Chem. Lett. / Search PubMed
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-7yxw:
Structure of the p22phox A200G mutant in complex with p47phox peptide
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / NADPH oxidase complex / oxidoreductase activator

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