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TitleStructural Basis of the Change in the Interaction Between Mycophenolic Acid and Subdomain IIA of Human Serum Albumin During Renal Failure.
Journal, issue, pagesJ. Med. Chem., Vol. 66, Page 951-961, Year 2023
Publish dateJan 12, 2022 (structure data deposition date)
AuthorsYamasaki, K. / Teshima, H. / Yukizawa, R. / Kuyama, K. / Tsukigawa, K. / Nishi, K. / Otagiri, M. / Kawai, A.
External linksJ. Med. Chem. / PubMed:36538495
MethodsX-ray diffraction
Resolution2.992 Å
Structure data

PDB-7wkz:
Crystal structure of the HSA complex with mycophenolate and aripiprazole
Method: X-RAY DIFFRACTION / Resolution: 2.992 Å

Chemicals

ChemComp-9SC:
7-[4-[4-[2,3-bis(chloranyl)phenyl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one / antipsychotic*YM

ChemComp-MOA:
MYCOPHENOLIC ACID / medication, immunosuppressant*YM

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / drug / complex

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