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TitleHistidine methyltransferase SETD3 methylates structurally diverse histidine mimics in actin.
Journal, issue, pagesProtein Sci., Vol. 31, Page e4305-e4305, Year 2022
Publish dateNov 22, 2021 (structure data deposition date)
AuthorsHintzen, J.C.J. / Ma, H. / Deng, H. / Witecka, A. / Andersen, S.B. / Drozak, J. / Guo, H. / Qian, P. / Li, H. / Mecinovic, J.
External linksProtein Sci. / PubMed:35481649
MethodsX-ray diffraction
Resolution1.79 - 2.9 Å
Structure data

PDB-7w28:
Crystal Structure of SETD3-SAH in complex with betaA-4PyrAla73 peptide
Method: X-RAY DIFFRACTION / Resolution: 1.79 Å

PDB-7w29:
Crystal Structure of SETD3-SAH in complex with betaA-Orn73 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / SET domain

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