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Structure paper

TitleStructural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use.
Journal, issue, pagesJ. Biomed. Sci., Vol. 29, Page 9-9, Year 2022
Publish dateNov 19, 2021 (structure data deposition date)
AuthorsTu, I.F. / Lin, T.L. / Yang, F.L. / Lee, I.M. / Tu, W.L. / Liao, J.H. / Ko, T.P. / Wu, W.J. / Jan, J.T. / Ho, M.R. ...Tu, I.F. / Lin, T.L. / Yang, F.L. / Lee, I.M. / Tu, W.L. / Liao, J.H. / Ko, T.P. / Wu, W.J. / Jan, J.T. / Ho, M.R. / Chou, C.Y. / Wang, A.H. / Wu, C.Y. / Wang, J.T. / Huang, K.F. / Wu, S.H.
External linksJ. Biomed. Sci. / PubMed:35130876
MethodsX-ray diffraction
Resolution1.46 - 2.78 Å
Structure data

PDB-7w1c:
Crystal structure of Klebsiella pneumoniae K1 capsule-specific polysaccharide lyase in a P1 crystal form
Method: X-RAY DIFFRACTION / Resolution: 1.48 Å

PDB-7w1d:
Crystal structure of Klebsiella pneumoniae K1 capsule-specific polysaccharide lyase in a C2 crystal form
Method: X-RAY DIFFRACTION / Resolution: 2.78 Å

PDB-7w1e:
Crystal structure of Klebsiella pneumoniae K1 capsule-specific polysaccharide lyase in complex with products
Method: X-RAY DIFFRACTION / Resolution: 1.46 Å

Chemicals

ChemComp-LMR:
(2S)-2-hydroxybutanedioic acid

ChemComp-IMD:
IMIDAZOLE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-CIT:
CITRIC ACID

ChemComp-CO3:
CARBONATE ION

ChemComp-98X:
2,6-anhydro-4,5-O-[(1R)-1-carboxyethylidene]-3-deoxy-L-threo-hex-2-enonic acid

Source
  • klebsiella phage ntuh-k2044-k1-1 (virus)
KeywordsVIRAL PROTEIN / BETA-HELIX / POLYSACCHARIDE LYASE / TAIL SPIKE PROTEIN / BETA-HELIX; POLYSACCHARIDE LYASE; TAIL SPIKE PROTEIN / LYASE

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