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-Structure paper
Title | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. |
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Journal, issue, pages | Jacs Au, Vol. 1, Page 2315-2327, Year 2021 |
Publish date | Aug 10, 2021 (structure data deposition date) |
![]() | Huang, K.W. / Chen, J.W. / Hua, T.Y. / Chu, Y.Y. / Chiu, T.Y. / Liu, J.Y. / Tu, C.I. / Hsu, K.C. / Kao, Y.T. / Chu, J.W. / Hsiao, Y.Y. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.8 - 2.403 Å |
Structure data | ![]() PDB-7v37: ![]() PDB-7v38: ![]() PDB-7v39: ![]() PDB-7v3a: ![]() PDB-7v3b: ![]() PDB-7v3c: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-HOH: ![]() ChemComp-PMB: ![]() ChemComp-HGB: ![]() ChemComp-MG: |
Source |
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![]() | VIRAL PROTEIN / DEDDh exonuclease / NP exonuclease / anti-viral drug / PCMPS / PCMB |