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-Structure paper
Title | Altered signaling at the PTH receptor via modified agonist contacts with the extracellular domain provides a path to prolonged agonism in vivo. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 119, Page e2212736119-e2212736119, Year 2022 |
Publish date | May 9, 2022 (structure data deposition date) |
![]() | Liu, S. / Yu, Z. / Daley, E.J. / Bingman, C.A. / Bruchs, A.T. / Gardella, T.J. / Gellman, S.H. |
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Methods | X-ray diffraction |
Resolution | 1.3 - 2.29 Å |
Structure data | ![]() PDB-7uzo: ![]() PDB-7uzp: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-HOH: ![]() ChemComp-EDO: |
Source |
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![]() | SIGNALING PROTEIN / parathyroid hormone 1 receptor / signaling / beta-amino acid |