Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Optimization of a switchable electrophile fragment into a potent and selective covalent inhibitor of human DDAH1
Journal, issue, pages	To Be Published
Publish date	Apr 5, 2022 (structure data deposition date)
Authors	Tuley, A. / Zheng, Y. / Tommasi, S. / Butrin, A. / May, K.V. / Ahn, Y. / Reidl, T.C. / Weerakoon, L. / Hulin, J. / Meech, R. ...Tuley, A. / Zheng, Y. / Tommasi, S. / Butrin, A. / May, K.V. / Ahn, Y. / Reidl, T.C. / Weerakoon, L. / Hulin, J. / Meech, R. / Patel, D.S. / Horton, C.P. / Swartzel, C.J. / Kim, Y. / Silverman, B.R. / Mangoni, A. / Liu, D. / Fast, W.
External links	Search PubMed
Methods	X-ray diffraction
Resolution	1.707 - 2.37 Å
Structure data	PDB-7ulu: Human DDAH1 soaked with its inhibitor ClPyrAA Method: X-RAY DIFFRACTION / Resolution: 2.2 Å PDB-7ulv: Human DDAH1 soaked with its inactivator S-((4-chloropyridin-2-yl)methyl)-L-cysteine Method: X-RAY DIFFRACTION / Resolution: 2.37 Å PDB-7ulx: Human DDAH1 soaked with its inhibitor N4-(4-chloropyridin-2-yl)-L-asparagine Method: X-RAY DIFFRACTION / Resolution: 1.707 Å
Chemicals	ChemComp-NOU: (2S)-2-amino-4-[(pyridin-2-yl)amino]butanoic acid ChemComp-HOH: WATER ChemComp-NO6: S-[(pyridin-2-yl)methyl]-L-cysteine ChemComp-NQ6: N-(pyridin-2-yl)-L-asparagine
Source	homo sapiens (human)
Keywords	HYDROLASE / DDAH1 / Dimethylargininase / DDAH / ClPyrAA / inactivator / S-((4-chloropyridin-2-yl)methyl)-L-cysteine / inhibitor / N4-(4-chloropyridin-2-yl)-L-asparagine