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-Structure paper
Title | Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome. |
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Journal, issue, pages | Nat. Struct. Mol. Biol., Vol. 29, Page 966-977, Year 2022 |
Publish date | Feb 4, 2022 (structure data deposition date) |
Authors | Bonsor, D.A. / Alexander, P. / Snead, K. / Hartig, N. / Drew, M. / Messing, S. / Finci, L.I. / Nissley, D.V. / McCormick, F. / Esposito, D. ...Bonsor, D.A. / Alexander, P. / Snead, K. / Hartig, N. / Drew, M. / Messing, S. / Finci, L.I. / Nissley, D.V. / McCormick, F. / Esposito, D. / Rodriguez-Viciana, P. / Stephen, A.G. / Simanshu, D.K. |
External links | Nat. Struct. Mol. Biol. / PubMed:36175670 |
Methods | X-ray diffraction |
Resolution | 2.17 - 2.4 Å |
Structure data | PDB-7tvf: PDB-7tvg: |
Chemicals | ChemComp-GOL: ChemComp-SO4: ChemComp-MN: ChemComp-NA: ChemComp-PO4: ChemComp-CL: ChemComp-GNP: ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | SIGNALING PROTEIN / Oncoprotein Phosphatase Scaffold protein Adaptor RAS Leucine rich repeat / Scaffold protein Adapter protein Leucine rich repeat Oncoprotein |