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-Structure paper
Title | Sculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation. |
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Journal, issue, pages | Bioconjug. Chem., Vol. 33, Page 1192-1200, Year 2022 |
Publish date | Feb 3, 2022 (structure data deposition date) |
Authors | Hwang, D. / Nilchan, N. / Park, H. / Roy, R.N. / Roush, W.R. / Rader, C. |
External links | Bioconjug. Chem. / PubMed:35584359 |
Methods | X-ray diffraction |
Resolution | 2.4 Å |
Structure data | PDB-7tus: |
Chemicals | ChemComp-PEG: ChemComp-SO4: ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / Antibody therapeutics / antibody-drug conjugate / catalytic antibody / protein modification / engineered cysteine |