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-Structure paper
Title | 5-Formyltetrahydrofolate promotes conformational remodeling in a methylenetetrahydrofolate reductase active site and inhibits its activity. |
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Journal, issue, pages | J. Biol. Chem., Vol. 299, Page 102855-102855, Year 2022 |
Publish date | Jan 10, 2022 (structure data deposition date) |
![]() | Yamada, K. / Mendoza, J. / Koutmos, M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.45 - 2.09 Å |
Structure data | ![]() PDB-7th4: ![]() PDB-7th5: ![]() PDB-8eac: |
Chemicals | ![]() ChemComp-FAD: ![]() ChemComp-FFO: ![]() ChemComp-CL: ![]() ChemComp-ACT: ![]() ChemComp-HOH: ![]() ChemComp-NA: |
Source |
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![]() | OXIDOREDUCTASE / TIM barrel / flavin / 5-formyltetrahydrofolate |