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TitleCo-crystal structure of human PRMT9 in complex with MT556 inhibitor
Journal, issue, pagesTo Be Published
Publish dateJul 6, 2021 (structure data deposition date)
AuthorsZeng, H. / Dong, A. / Hutchinson, A. / Seitova, A. / Li, Y. / Gao, Y.D. / Schneider, S. / Siliphaivanh, P. / Sloman, D. / Nicholson, B. ...Zeng, H. / Dong, A. / Hutchinson, A. / Seitova, A. / Li, Y. / Gao, Y.D. / Schneider, S. / Siliphaivanh, P. / Sloman, D. / Nicholson, B. / Fischer, C. / Hicks, J. / Brown, P.J. / Arrowsmith, C.H. / Edwards, A.M. / Halabelian, L. / Structural Genomics Consortium (SGC)
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-7rbq:
Co-crystal structure of human PRMT9 in complex with MT556 inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-44T:
7-[5-S-(4-{[(4-ethylpyridin-3-yl)methyl]amino}butyl)-5-thio-beta-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-UNX:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / PRMT9 / MT556 inhibitor / structural genomics / structural genomics consortium / SGC / TRANSFERASE-TRANSFERASE INHIBITOR complex

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