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-Structure paper
Title | Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation. |
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Journal, issue, pages | J. Biol. Chem., Vol. 298, Page 101985-101985, Year 2022 |
Publish date | Sep 17, 2021 (structure data deposition date) |
![]() | Nagy, Z.A. / Heja, D. / Bencze, D. / Kiss, B. / Boros, E. / Szakacs, D. / Fodor, K. / Wilmanns, M. / Kocsis, A. / Dobo, J. ...Nagy, Z.A. / Heja, D. / Bencze, D. / Kiss, B. / Boros, E. / Szakacs, D. / Fodor, K. / Wilmanns, M. / Kocsis, A. / Dobo, J. / Gal, P. / Harmat, V. / Pal, G. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.40001520992 - 3.39 Å |
Structure data | ![]() PDB-7pqn: ![]() PDB-7pqo: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-NA: |
Source |
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![]() | IMMUNE SYSTEM / serine protease / complement / inhibitor |