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-Structure paper
Title | Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen |
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Journal, issue, pages | Nat Commun, Vol. 13, Page 5333-, Year 2022 |
Publish date | Jun 16, 2021 (structure data deposition date) |
![]() | Poole, A. / Karuppiah, V. / Hartt, A. / Haidar, J.N. / Moureau, S. / Dobrzycki, T. / Hayes, C. / Rowley, C. / Dias, J. / Harper, S. ...Poole, A. / Karuppiah, V. / Hartt, A. / Haidar, J.N. / Moureau, S. / Dobrzycki, T. / Hayes, C. / Rowley, C. / Dias, J. / Harper, S. / Barnbrook, K. / Hock, M. / Coles, C. / Yang, W. / Aleksic, M. / Lin, A.B. / Robinson, R. / Dukes, J.D. / Liddy, N. / Van der Kamp, M. / Plowman, G.D. / Vuidepot, A. / Cole, D.K. / Whale, A.D. / Chillakuri, C. |
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Methods | X-ray diffraction |
Resolution | 1.81 - 3.41 Å |
Structure data | ![]() PDB-7ow3: ![]() PDB-7ow4: ![]() PDB-7ow5: ![]() PDB-7ow6: ![]() PDB-7pb2: |
Chemicals | ![]() ChemComp-HOH: ![]() ChemComp-SO4: |
Source |
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![]() | IMMUNE SYSTEM / HLA / KRAS / TCR / T cell receptor |