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-Structure paper
Title | Identification of the first structurally validated covalent ligands of the small GTPase RAB27A. |
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Journal, issue, pages | Rsc Med Chem, Vol. 13, Page 150-155, Year 2022 |
Publish date | Jun 1, 2021 (structure data deposition date) |
Authors | Jamshidiha, M. / Lanyon-Hogg, T. / Sutherell, C.L. / Craven, G.B. / Tersa, M. / De Vita, E. / Brustur, D. / Perez-Dorado, I. / Hassan, S. / Petracca, R. ...Jamshidiha, M. / Lanyon-Hogg, T. / Sutherell, C.L. / Craven, G.B. / Tersa, M. / De Vita, E. / Brustur, D. / Perez-Dorado, I. / Hassan, S. / Petracca, R. / Morgan, R.M. / Sanz-Hernandez, M. / Norman, J.C. / Armstrong, A. / Mann, D.J. / Cota, E. / Tate, E.W. |
External links | Rsc Med Chem / PubMed:35308027 |
Methods | X-ray diffraction |
Resolution | 2.23 - 2.32 Å |
Structure data | PDB-7opp: PDB-7opq: PDB-7opr: |
Chemicals | ChemComp-GNP: ChemComp-MG: ChemComp-HOH: ChemComp-06D: ChemComp-GOL: ChemComp-05Y: |
Source |
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Keywords | EXOCYTOSIS / Rab27 / GTPase / Slp2a / exosome / Acrylamide / Cysteine-reactive |