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Structure paper

TitleStructure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension.
Journal, issue, pagesNat. Chem. Biol., Vol. 18, Page 422-431, Year 2022
Publish dateMay 17, 2021 (structure data deposition date)
AuthorsNakasone, M.A. / Majorek, K.A. / Gabrielsen, M. / Sibbet, G.J. / Smith, B.O. / Huang, D.T.
External linksNat. Chem. Biol. / PubMed:35027744
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-7ojx:
E2 UBE2K covalently linked to donor Ub, acceptor di-Ub, and RING E3 primed for K48-linked Ub chain synthesis
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-ME7:
1,1'-ethane-1,2-diylbis(1H-pyrrole-2,5-dione)

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLIGASE / UBIQUITIN / RING E3 / E2

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