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-Structure paper
Title | ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes. |
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Journal, issue, pages | Cell Rep, Vol. 37, Page 109834-109834, Year 2021 |
Publish date | Apr 6, 2021 (structure data deposition date) |
![]() | Shi, F. / Mendrola, J.M. / Sheetz, J.B. / Wu, N. / Sommer, A. / Speer, K.F. / Noordermeer, J.N. / Kan, Z.Y. / Perry, K. / Englander, S.W. ...Shi, F. / Mendrola, J.M. / Sheetz, J.B. / Wu, N. / Sommer, A. / Speer, K.F. / Noordermeer, J.N. / Kan, Z.Y. / Perry, K. / Englander, S.W. / Stayrook, S.E. / Fradkin, L.G. / Lemmon, M.A. |
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Methods | X-ray diffraction |
Resolution | 1.75 - 2 Å |
Structure data | ![]() PDB-7me4: ![]() PDB-7me5: |
Chemicals | ![]() ChemComp-PAM: ![]() ChemComp-HOH: ![]() ChemComp-NAG: |
Source |
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![]() | SIGNALING PROTEIN / WNT signaling / receptor tyrosine kinases / acylation / growth factor signaling / co-receptor / pseudokinases / ligand / receptor / cancer |