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-Structure paper
Title | Identification of Potent Reverse Indazole Inhibitors for HPK1. |
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Journal, issue, pages | Acs Med. Chem. Lett., Vol. 12, Page 459-466, Year 2021 |
Publish date | Dec 16, 2020 (structure data deposition date) |
![]() | Yu, E.C. / Methot, J.L. / Fradera, X. / Lesburg, C.A. / Lacey, B.M. / Siliphaivanh, P. / Liu, P. / Smith, D.M. / Xu, Z. / Piesvaux, J.A. ...Yu, E.C. / Methot, J.L. / Fradera, X. / Lesburg, C.A. / Lacey, B.M. / Siliphaivanh, P. / Liu, P. / Smith, D.M. / Xu, Z. / Piesvaux, J.A. / Kawamura, S. / Xu, H. / Miller, J.R. / Bittinger, M. / Pasternak, A. |
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Methods | X-ray diffraction |
Resolution | 1.85 - 2.68 Å |
Structure data | ![]() PDB-7l24: ![]() PDB-7l25: ![]() PDB-7l26: |
Chemicals | ![]() ChemComp-XHV: ![]() ChemComp-HOH: ![]() ChemComp-XHS: ![]() ChemComp-EDO: ![]() ChemComp-XHM: |
Source |
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![]() | TRANSFERASE / HPK1 HEMATOPOIETIC PROGENITOR KINASE / INHIBITOR COMPLEX / TRANSFERASE/TRANSFERASE inhibitor / TRANSFERASE-TRANSFERASE inhibitor complex |