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Structure paper

TitleThe ligand-induced structural changes of human L-Arginine:Glycine amidinotransferase. A mutational and crystallographic study.
Journal, issue, pagesJ. Biol. Chem., Vol. 274, Page 3026-3032, Year 1999
Publish dateOct 12, 1998 (structure data deposition date)
AuthorsFritsche, E. / Humm, A. / Huber, R.
External linksJ. Biol. Chem. / PubMed:9915841
MethodsX-ray diffraction
Resolution2.3 - 2.9 Å
Structure data

PDB-1jdx:
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH L-NORVALINE
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-2jdx:
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE, DELETIONMUTANT ATDELTAM302
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-5jdw:
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH GLYCINE
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-6jdw:
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH GAMMA-AMINO BUTYRIC ACID
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-7jdw:
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH DELTA-AMINO VALERIC ACID
Method: X-RAY DIFFRACTION / Resolution: 2.37 Å

PDB-8jdw:
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH L-ALANINE
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-9jdw:
CRYSTAL STRUCTURE OF HUMAN L-ARGININE:GLYCINE AMIDINOTRANSFERASE IN COMPLEX WITH ALPHA-AMINO BUTYRIC ACID
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-NVA:
NORVALINE

ChemComp-HOH:
WATER

ChemComp-GLY:
GLYCINE

ChemComp-ABU:
GAMMA-AMINO-BUTANOIC ACID

ChemComp-DAV:
DELTA-AMINO VALERIC ACID

ChemComp-ALA:
ALANINE

ChemComp-ABA:
ALPHA-AMINOBUTYRIC ACID

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / CREATINE BIOSYNTHESIS / CATALYTIC TRIAD / REACTION MECHANISM / NOVEL FOLD / FIVEFOLD PSEUDOSYMMETRY

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