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-Structure paper
Title | Structural insights into the clustering and activation of Tie2 receptor mediated by Tie2 agonistic antibody. |
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Journal, issue, pages | Nat Commun, Vol. 12, Page 6287-6287, Year 2021 |
Publish date | Feb 25, 2021 (structure data deposition date) |
Authors | Jo, G. / Bae, J. / Hong, H.J. / Han, A.R. / Kim, D.K. / Hong, S.P. / Kim, J.A. / Lee, S. / Koh, G.Y. / Kim, H.M. |
External links | Nat Commun / PubMed:34725372 |
Methods | X-ray diffraction |
Resolution | 2.094 Å |
Structure data | PDB-7e72: |
Chemicals | ChemComp-EDO: ChemComp-HOH: |
Source |
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Keywords | MEMBRANE PROTEIN / antigen-antibody complex / agonistic antibody / angiogenesis / vascular stabilization / receptor tyrosine kinase / Tie2 |