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-Structure paper
Title | State-selective modulation of heterotrimeric G alpha s signaling with macrocyclic peptides. |
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Journal, issue, pages | Cell, Year 2022 |
Publish date | Mar 22, 2020 (structure data deposition date) |
![]() | Dai, S.A. / Hu, Q. / Gao, R. / Blythe, E.E. / Touhara, K.K. / Peacock, H. / Zhang, Z. / von Zastrow, M. / Suga, H. / Shokat, K.M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.57 - 1.95 Å |
Structure data | ![]() PDB-7bph: ![]() PDB-7e5e: |
Chemicals | ![]() ChemComp-GNP: ![]() ChemComp-MG: ![]() ChemComp-GOL: ![]() ChemComp-CL: ![]() ChemComp-HOH: ![]() ChemComp-GDP: |
Source |
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![]() | SIGNALING PROTEIN / G protein / GNAS / adenylyl cyclase / active state / inhibitor / mRNA display / RaPID / cyclic peptide / GsIN-1 / inactive state / GD20 |