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Structure paper

TitleStructure of the dopamine D 2 receptor in complex with the antipsychotic drug spiperone.
Journal, issue, pagesNat Commun, Vol. 11, Page 6442-6442, Year 2020
Publish dateNov 9, 2020 (structure data deposition date)
AuthorsIm, D. / Inoue, A. / Fujiwara, T. / Nakane, T. / Yamanaka, Y. / Uemura, T. / Mori, C. / Shiimura, Y. / Kimura, K.T. / Asada, H. ...Im, D. / Inoue, A. / Fujiwara, T. / Nakane, T. / Yamanaka, Y. / Uemura, T. / Mori, C. / Shiimura, Y. / Kimura, K.T. / Asada, H. / Nomura, N. / Tanaka, T. / Yamashita, A. / Nango, E. / Tono, K. / Kadji, F.M.N. / Aoki, J. / Iwata, S. / Shimamura, T.
External linksNat Commun / PubMed:33353947
MethodsX-ray diffraction
Resolution3.1 Å
Structure data

PDB-7dfp:
Human dopamine D2 receptor in complex with spiperone
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-SIP:
8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one / antipsychotic*YM

Source
  • homo sapiens (human)
  • escherichia coli (E. coli)
  • mus musculus (house mouse)
KeywordsMEMBRANE PROTEIN / G-protein coupled receptor / Dopamine receptor / Spiperone / antipsychotic / Schizophrenia

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