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Structure paper

TitleFECH - inhibitor complex 1
Journal, issue, pagesto be published
Publish dateAug 18, 2020 (structure data deposition date)
AuthorsLee, S.J. / Park, J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-7ct7:
FECH - inhibitor complex 2
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-7ctc:
FECH - inhibitor complex 1
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-FES:
FE2/S2 (INORGANIC) CLUSTER

ChemComp-GF9:
2-[[(4-chlorophenyl)amino]methyl]-5-propyl-6H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one

ChemComp-HOH:
WATER

ChemComp-GFO:
2-(4-tert-butylphenyl)-5-[(quinolin-2-ylamino)methyl]-6H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / heme synthesis enzyme porphyrin binding FECH inhibitor ocular neovascularization

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