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-Structure paper
Title | Piperidine-4-carboxamide as a new scaffold for designing secretory glutaminyl cyclase inhibitors. |
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Journal, issue, pages | Int. J. Biol. Macromol., Vol. 170, Page 415-423, Year 2020 |
Publish date | Aug 5, 2020 (structure data deposition date) |
Authors | Dileep, K.V. / Sakai, N. / Ihara, K. / Kato-Murayama, M. / Nakata, A. / Ito, A. / Sivaraman, D.M. / Shin, J.W. / Yoshida, M. / Shirouzu, M. / Zhang, K.Y.J. |
External links | Int. J. Biol. Macromol. / PubMed:33373636 |
Methods | X-ray diffraction |
Resolution | 1.7 - 1.85 Å |
Structure data | PDB-7coz: PDB-7cp0: |
Chemicals | ChemComp-ZN: ChemComp-SO4: ChemComp-Q39: ChemComp-EDO: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / Glutaminyl-peptide cyclotransferase / sQC / Alzheimer's disease / Pyroglutamate |