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TitlePotent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2.
Journal, issue, pagesNat Commun, Vol. 12, Page 4210-4210, Year 2021
Publish dateJul 6, 2020 (structure data deposition date)
AuthorsZhang, Q. / Ju, B. / Ge, J. / Chan, J.F. / Cheng, L. / Wang, R. / Huang, W. / Fang, M. / Chen, P. / Zhou, B. ...Zhang, Q. / Ju, B. / Ge, J. / Chan, J.F. / Cheng, L. / Wang, R. / Huang, W. / Fang, M. / Chen, P. / Zhou, B. / Song, S. / Shan, S. / Yan, B. / Zhang, S. / Ge, X. / Yu, J. / Zhao, J. / Wang, H. / Liu, L. / Lv, Q. / Fu, L. / Shi, X. / Yuen, K.Y. / Wang, Y. / Chen, Z. / Zhang, L. / Wang, X. / Zhang, Z.
External linksNat Commun / PubMed:34244522
MethodsX-ray diffraction
Resolution2.357 - 2.561 Å
Structure data

PDB-7cho:
Crystal structure of SARS-CoV-2 antibody P5A-1D2 with RBD
Method: X-RAY DIFFRACTION / Resolution: 2.561 Å

PDB-7chp:
Crystal structure of SARS-CoV-2 antibody P5A-3C8 with RBD
Method: X-RAY DIFFRACTION / Resolution: 2.357 Å

PDB-7chs:
Crystal structure of SARS-CoV-2 antibody P22A-1D1 with RBD
Method: X-RAY DIFFRACTION / Resolution: 2.401 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • severe acute respiratory syndrome coronavirus 2
  • homo sapiens (human)
KeywordsVIRAL PROTEIN / spike / receptor binding domain / antibody

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