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Structure paper

TitleTwo-Dimensional Design Strategy to Construct Smart Fluorescent Probes for the Precise Tracking of Senescence.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 60, Page 10756-10765, Year 2021
Publish dateMar 30, 2020 (structure data deposition date)
AuthorsGao, Y. / Hu, Y. / Liu, Q. / Li, X. / Kim, C.Y. / James, T.D. / Li, J. / Chen, X. / Guo, Y.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:33624914
MethodsX-ray diffraction
Resolution2.67 - 2.7 Å
Structure data

PDB-7brs:
E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSA02
Method: X-RAY DIFFRACTION / Resolution: 2.67 Å

PDB-7btk:
E.coli beta-galactosidase (E537Q) in complex with fluorescent probe KSA01
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-F4X:
8-[2-[(E)-2-[4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethenyl]-3,3-dimethyl-indol-1-ium-1-yl]octanoic acid

ChemComp-MG:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-F6L:
4-[[2-[(E)-2-[4-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxyphenyl]ethenyl]-3,3-dimethyl-2H-indol-1-yl]methyl]benzoic acid

Source
  • escherichia coli k-12 (bacteria)
KeywordsHYDROLASE / beta_galactosidase / fluorescent probe

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