Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity.
Journal, issue, pages	J. Biol. Chem., Vol. 296, Page 100568-100568, Year 2021
Publish date	Dec 7, 2020 (structure data deposition date)
Authors	Rehling, D. / Zhang, S.M. / Jemth, A.S. / Koolmeister, T. / Throup, A. / Wallner, O. / Scaletti, E. / Moriyama, T. / Nishii, R. / Davies, J. ...Rehling, D. / Zhang, S.M. / Jemth, A.S. / Koolmeister, T. / Throup, A. / Wallner, O. / Scaletti, E. / Moriyama, T. / Nishii, R. / Davies, J. / Desroses, M. / Rudd, S.G. / Scobie, M. / Homan, E. / Berglund, U.W. / Yang, J.J. / Helleday, T. / Stenmark, P.
External links	J. Biol. Chem. / PubMed:33753169
Methods	X-ray diffraction
Resolution	1.45 - 1.6 Å
Structure data	PDB-7b63: Structure of NUDT15 in complex with TH7755 Method: X-RAY DIFFRACTION / Resolution: 1.6 Å PDB-7b64: Structure of NUDT15 V18I Mutant in complex with TH7755 Method: X-RAY DIFFRACTION / Resolution: 1.5 Å PDB-7b65: Structure of NUDT15 R139C Mutant in complex with TH7755 Method: X-RAY DIFFRACTION / Resolution: 1.6 Å PDB-7b66: Structure of NUDT15 R139H Mutant in complex with TH7755 Method: X-RAY DIFFRACTION / Resolution: 1.6 Å PDB-7b67: Structure of NUDT15 V18_V19insGV Mutant in complex with TH7755 Method: X-RAY DIFFRACTION / Resolution: 1.45 Å
Chemicals	ChemComp-SYW: (R)-6-((2-methyl-4-(1-methyl-1H-indole-5-carbonyl)piperazin-1-yl)sulfonyl)benzo[d]oxazol-2(3H)-one ChemComp-MG: Unknown entry ChemComp-HOH: WATER ChemComp-PO4: PHOSPHATE ION
Source	homo sapiens (human)
Keywords	HYDROLASE / Inhibitor / complex / Nucleoside Triphosphate Pyrophosphohydrolase