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-Structure paper
Title | Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A 4 Hydrolase. |
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Journal, issue, pages | J. Med. Chem., Vol. 64, Page 1889-1903, Year 2021 |
Publish date | Nov 3, 2020 (structure data deposition date) |
![]() | Markert, C. / Thoma, G. / Srinivas, H. / Bollbuck, B. / Luond, R.M. / Miltz, W. / Walchli, R. / Wolf, R. / Hinrichs, J. / Bergsdorf, C. ...Markert, C. / Thoma, G. / Srinivas, H. / Bollbuck, B. / Luond, R.M. / Miltz, W. / Walchli, R. / Wolf, R. / Hinrichs, J. / Bergsdorf, C. / Azzaoui, K. / Penno, C.A. / Klein, K. / Wack, N. / Jager, P. / Hasler, F. / Beerli, C. / Loetscher, P. / Dawson, J. / Wieczorek, G. / Numao, S. / Littlewood-Evans, A. / Rohn, T.A. |
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Methods | X-ray diffraction |
Resolution | 1.79 - 1.95 Å |
Structure data | ![]() PDB-7auz: ![]() PDB-7av0: ![]() PDB-7av1: ![]() PDB-7av2: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-ACT: ![]() ChemComp-YB: ![]() ChemComp-IMD: ![]() ChemComp-RZE: ![]() ChemComp-HOH: ![]() ChemComp-RZB: ![]() ChemComp-RZK: ![]() ChemComp-RZN: |
Source |
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![]() | HYDROLASE / inhibitor / complex |