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TitleMechanism of chorismate dehydratase MqnA, the first enzyme of the futalosine pathway, proceeds via substrate-assisted catalysis.
Journal, issue, pagesJ. Biol. Chem., Vol. 298, Page 102601-102601, Year 2022
Publish dateOct 11, 2020 (structure data deposition date)
AuthorsPrasad, A. / Breithaupt, C. / Nguyen, D.A. / Lilie, H. / Ziegler, J. / Stubbs, M.T.
External linksJ. Biol. Chem. / PubMed:36265588
MethodsX-ray diffraction
Resolution1.917 - 2.11 Å
Structure data

PDB-7an9:
Enzyme of biosynthetic pathway
Method: X-RAY DIFFRACTION / Resolution: 2.11 Å

PDB-7ywc:
Enzyme of biosynthetic pathway
Method: X-RAY DIFFRACTION / Resolution: 1.917 Å

Chemicals

ChemComp-RDH:
3-[(1-Carboxyvinyl)oxy]benzoic acid

ChemComp-HOH:
WATER

ChemComp-ISJ:
(3R,4R)-3-[(1-carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid

ChemComp-GOL:
GLYCEROL

Source
  • streptomyces coelicolor a3(2) (bacteria)
  • streptomyces coelicolor (bacteria)
KeywordsBIOSYNTHETIC PROTEIN / Enzyme activity / Biosynthetic pathway

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