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-Structure paper
Title | Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of R p - and S p -dNTP alpha S Diastereomers. |
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Journal, issue, pages | Biochemistry, Vol. 60, Page 1682-1698, Year 2021 |
Publish date | Aug 24, 2020 (structure data deposition date) |
![]() | Morris, E.R. / Kunzelmann, S. / Caswell, S.J. / Purkiss, A.G. / Kelly, G. / Taylor, I.A. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.29 Å |
Structure data | ![]() PDB-7a5y: |
Chemicals | ![]() ChemComp-FE: ![]() ChemComp-MG: ![]() ChemComp-T8T: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / triphosphohydrolase / metallo-enzyme / binuclear / HD |