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-Structure paper
Title | Structure of an ancestral ADP-dependent kinase with fructose-6P reveals key residues for binding, catalysis, and ligand-induced conformational changes. |
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Journal, issue, pages | J. Biol. Chem., Vol. 296, Page 100219-100219, Year 2020 |
Publish date | Jun 20, 2020 (structure data deposition date) |
Authors | Munoz, S.M. / Castro-Fernandez, V. / Guixe, V. |
External links | J. Biol. Chem. / PubMed:33839685 |
Methods | X-ray diffraction |
Resolution | 3.12 Å |
Structure data | PDB-6xio: |
Chemicals | ChemComp-AT4: ChemComp-F6P: ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / ancestral protein reconstruction / ADP-dependent sugar kinases family / glucokinase / phosphofructokinase / enzyme evolution |