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-Structure paper
Title | Insights into the importance of WPD-loop sequence for activity and structure in protein tyrosine phosphatases. |
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Journal, issue, pages | Chem Sci, Vol. 13, Page 13524-13540, Year 2022 |
Publish date | Jun 12, 2020 (structure data deposition date) |
![]() | Shen, R. / Crean, R.M. / Olsen, K.J. / Corbella, M. / Calixto, A.R. / Richan, T. / Brandao, T.A.S. / Berry, R.D. / Tolman, A. / Loria, J.P. ...Shen, R. / Crean, R.M. / Olsen, K.J. / Corbella, M. / Calixto, A.R. / Richan, T. / Brandao, T.A.S. / Berry, R.D. / Tolman, A. / Loria, J.P. / Johnson, S.J. / Kamerlin, S.C.L. / Hengge, A.C. |
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Methods | X-ray diffraction |
Resolution | 1.549 - 2.549 Å |
Structure data | ![]() PDB-6xe8: ![]() PDB-6xea: ![]() PDB-6xed: ![]() PDB-6xee: ![]() PDB-6xef: ![]() PDB-6xeg: ![]() PDB-7s4f: |
Chemicals | ![]() ChemComp-BEN: ![]() ChemComp-TRS: ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-VO4: ![]() ChemComp-WO4: ![]() ChemComp-PEG: ![]() ChemComp-EPE: ![]() ChemComp-GOL: |
Source |
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![]() | HYDROLASE / PTP1B / tyrosine phosphatase / WPD loop / STRUCTURAL PROTEIN / P-loop / WPD-loops / Hepes / Protein Phosphatase / EGFR receptor / Phosphoprotein |