EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A.
ジャーナル・号・ページ	J. Med. Chem., Vol. 63, Page 11100-11120, Year 2020
掲載日	2020年6月8日 (構造データの登録日)
著者	Lin, L. / Olson, M.E. / Sugane, T. / Turner, L.D. / Tararina, M.A. / Nielsen, A.L. / Kurbanov, E.K. / Pellett, S. / Johnson, E.A. / Cohen, S.M. ...Lin, L. / Olson, M.E. / Sugane, T. / Turner, L.D. / Tararina, M.A. / Nielsen, A.L. / Kurbanov, E.K. / Pellett, S. / Johnson, E.A. / Cohen, S.M. / Allen, K.N. / Janda, K.D.
リンク	J. Med. Chem. / PubMed:32886509
手法	X線回折
解像度	1.68 - 2.5 Å
構造データ	PDB-6xcb: Structure of the C. botulinum neurotoxin serotype A light chain protease in complex with covalent inhibitor 20 手法: X-RAY DIFFRACTION / 解像度: 1.74 Å PDB-6xcc: Structure of the C. botulinum neurotoxin serotype A light chain protease in complex with covalent inhibitor 21 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-6xcd: Structure of the C. botulinum neurotoxin serotype A light chain protease in complex with covalent inhibitor 22 手法: X-RAY DIFFRACTION / 解像度: 1.92 Å PDB-6xce: Structure of the C. botulinum neurotoxin serotype A light chain protease in complex with covalent inhibitor 53 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-6xcf: Structure of the C. botulinum neurotoxin serotype A light chain protease in complex with noncovalent inhibitor 59 手法: X-RAY DIFFRACTION / 解像度: 1.68 Å
化合物	ChemComp-ZN: Unknown entry ChemComp-UZY: N-hydroxy-6-sulfanylhexanamide ChemComp-HOH: WATER ChemComp-UZV: N-hydroxy-5-sulfanylpentanamide ChemComp-UZS: N-hydroxy-7-sulfanylheptanamide ChemComp-UZM: (3S)-3-(2,4-dichlorophenyl)-N~1~-hydroxy-N~5~-(3-sulfanylpropyl)pentanediamide ChemComp-UZP: (3R)-3-(2,4-dichlorophenyl)-N~1~-hydroxy-N~5~-pentylpentanediamide
由来	clostridium botulinum (ボツリヌス菌)
キーワード	TOXIN/INHIBITOR / covalent inhibitor / hydroxamate / TOXIN / TOXIN-INHIBITOR complex