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Structure paper

TitleBiochemical basis for the regulation of biosynthesis of antiparasitics by bacterial hormones.
Journal, issue, pagesElife, Vol. 9, Year 2020
Publish dateApr 26, 2020 (structure data deposition date)
AuthorsKapoor, I. / Olivares, P. / Nair, S.K.
External linksElife / PubMed:32510324
MethodsX-ray diffraction
Resolution2 - 3.09 Å
Structure data

PDB-6wp7:
Avenolide Binding Autoregulator AvaR1
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-6wp9:
AvaR1 bound to Avenolide
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-6wpa:
Structure of AvaR1 bound to DNA half-site
Method: X-RAY DIFFRACTION / Resolution: 3.09 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-XVR:
(5S)-5-[(6R)-6-hydroxy-6-methyl-5-oxooctyl]furan-2(5H)-one

Source
  • streptomyces avermitilis (bacteria)
  • streptomyces avermitilis ma-4680 = nbrc 14893 (bacteria)
KeywordsDNA BINDING PROTEIN / Transcriptional Repressor / DNA BINDING PROTEIN/HORMONE / Transcriptional Repressor bound ligand / DNA BINDING PROTEIN-INHIBITOR complex / DNA BINDING PROTEIN-HORMONE complex / DNA BINDING PROTEIN/DNA / DNA oligonucleotide / DNA-Protein biniding / DNA BINDING PROTEIN-DNA complex

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