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-Structure paper
Title | Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling. |
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Journal, issue, pages | Cell Rep, Vol. 31, Page 107809-107809, Year 2020 |
Publish date | Nov 12, 2019 (structure data deposition date) |
![]() | Holden, J.K. / Crawford, J.J. / Noland, C.L. / Schmidt, S. / Zbieg, J.R. / Lacap, J.A. / Zang, R. / Miller, G.M. / Zhang, Y. / Beroza, P. ...Holden, J.K. / Crawford, J.J. / Noland, C.L. / Schmidt, S. / Zbieg, J.R. / Lacap, J.A. / Zang, R. / Miller, G.M. / Zhang, Y. / Beroza, P. / Reja, R. / Lee, W. / Tom, J.Y.K. / Fong, R. / Steffek, M. / Clausen, S. / Hagenbeek, T.J. / Hu, T. / Zhou, Z. / Shen, H.C. / Cunningham, C.N. |
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Methods | X-ray diffraction |
Resolution | 1.543 - 1.658 Å |
Structure data | ![]() PDB-6uyb: ![]() PDB-6uyc: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-QSJ: ![]() ChemComp-TRS: ![]() ChemComp-HOH: ![]() ChemComp-QLV: |
Source |
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![]() | Transcription/Transcription Inhibitor / EAD / YAP Binding Domain / Transcription Inhibitor / Palmitoylation inhibitor / Transcription-Transcription Inhibitor complex / TRANSCRIPTION/INHIBITOR / TEAD / TRANSCRIPTION-INHIBITOR complex |