Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	In crystallo-screening for discovery of human norovirus 3C-like protease inhibitors.
Journal, issue, pages	J Struct Biol X, Vol. 4, Page 100031-100031, Year 2020
Publish date	Oct 5, 2019 (structure data deposition date)
Authors	Guo, J. / Douangamath, A. / Song, W. / Coker, A.R. / Chan, A.W.E. / Wood, S.P. / Cooper, J.B. / Resnick, E. / London, N. / Delft, F.V.
External links	J Struct Biol X / PubMed:32743543
Methods	X-ray diffraction
Resolution	1.3 - 2.07 Å
Structure data	PDB-6t1q: 3C-like protease from Southampton norovirus. Method: X-RAY DIFFRACTION / Resolution: 1.3 Å PDB-6t2i: 3C-like protease from Southampton virus complexed with FMOPL000157a. Method: X-RAY DIFFRACTION / Resolution: 1.61 Å PDB-6t2x: 3C-like protease from Southampton virus complexed with FMOPL000004a. Method: X-RAY DIFFRACTION / Resolution: 1.54 Å PDB-6t3g: 3C-like protease from Southampton virus complexed with FMOPL000324a. Method: X-RAY DIFFRACTION / Resolution: 1.63 Å PDB-6t49: 3C-like protease from Southampton virus complexed with FMOPL000582a. Method: X-RAY DIFFRACTION / Resolution: 1.56 Å PDB-6t4e: Native C3-like protease from Southampton virus complexed with FMOPL000287a. Method: X-RAY DIFFRACTION / Resolution: 1.66 Å PDB-6t4s: 3C-like protease from Southampton virus complexed with FMOPL000013a. Method: X-RAY DIFFRACTION / Resolution: 2.02 Å PDB-6t5d: 3C-like protease from Southampton virus complexed with FMOPL000014a. Method: X-RAY DIFFRACTION / Resolution: 1.42 Å PDB-6t5r: 3C-like protease from Southampton virus complexed with FMOPL000091a. Method: X-RAY DIFFRACTION / Resolution: 1.78 Å PDB-6t6w: 3C-like protease from Southampton virus complexed with XST00000692b. Method: X-RAY DIFFRACTION / Resolution: 1.8 Å PDB-6t71: 3C-like protease from Southampton virus complexed with XST00000375b. Method: X-RAY DIFFRACTION / Resolution: 1.52 Å PDB-6t82: 3C-like protease from Southampton virus complexed with FMOPL000542a. Method: X-RAY DIFFRACTION / Resolution: 1.46 Å PDB-6t8r: 3C-like protease from Southampton virus complexed with FMOPL000605a. Method: X-RAY DIFFRACTION / Resolution: 1.88 Å PDB-6t8t: 3C-like protease from Southampton virus complexed with FMOPL000603a. Method: X-RAY DIFFRACTION / Resolution: 1.68 Å PDB-6tal: 3C-like protease from Southampton virus complexed with FMOPL000227a. Method: X-RAY DIFFRACTION / Resolution: 1.51 Å PDB-6taw: 3C-like protease from Southampton virus complexed with FMOPL000411a. Method: X-RAY DIFFRACTION / Resolution: 1.41 Å PDB-6tbo: 3C-like protease from Southampton virus complexed with FMOPL000363a. Method: X-RAY DIFFRACTION / Resolution: 2.07 Å PDB-6tbp: 3C-like protease from Southampton virus complexed with FMOPL000490a. Method: X-RAY DIFFRACTION / Resolution: 1.56 Å PDB-6tc1: 3C-like protease from Southampton virus complexed with FMOPL000283a. Method: X-RAY DIFFRACTION / Resolution: 1.67 Å PDB-6tcf: 3C-like protease from Southampton virus complexed with XST00000642b. Method: X-RAY DIFFRACTION / Resolution: 1.79 Å PDB-6tgl: 3c-like protease from Southampton virus complexed with FMOPL000644a. Method: X-RAY DIFFRACTION / Resolution: 1.99 Å
Chemicals	ChemComp-HOH: WATER / Water ChemComp-JFM: N-(2-phenylethyl)methanesulfonamide ChemComp-DMS: DIMETHYL SULFOXIDE / DMSO, precipitantYM / Dimethyl sulfoxide ChemComp-PO4: PHOSPHATE ION / Phosphate ChemComp-JFJ: 1-(3-chlorophenyl)-N-methylmethanamine ChemComp-JOV: 3-chloro-N-(1-hydroxy-2-methylpropan-2-yl)benzamide ChemComp-MH5: 3-[(5-methylthiophen-2-yl)methylamino]benzoic acid ChemComp-HWH: ~{N}-[2-(5-fluoranyl-1~{H}-indol-3-yl)ethyl]ethanamide ChemComp-K2P: 2-(trifluoromethoxy)benzoic acid ChemComp-MJW: 2-phenylmethoxyaniline ChemComp-MKN: 3-(5-thiophen-2-ylthiophen-2-yl)-1~{H}-pyrazole ChemComp-JL7: 2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4-carboxylic acid ChemComp-MQB: 2-(1-benzofuran-3-yl)ethanoic acid ChemComp-MUK: 4,6-dimethyl-~{N}-phenyl-pyrimidin-2-amine / Pyrimethanil ChemComp-GVY: 4-(5-amino-1,3,4-thiadiazol-2-yl)phenol ChemComp-YI6: 2-(4-ethoxyphenyl)ethanoic acid ChemComp-TFA: trifluoroacetic acid / Trifluoroacetic acid ChemComp-MZW: 5-ethyl-1,3,4-thiadiazol-2-amine ChemComp-N08: ~{N}-[2-(4-fluorophenyl)ethyl]furan-2-carboxamide ChemComp-N0E: ~{N}-(4-hydroxyphenyl)-3-phenyl-propanamide ChemComp-N0H: ~{N}-(2-hydroxyphenyl)-2-phenoxy-ethanamide ChemComp-N1E: methyl quinoline-6-carboxylate ChemComp-LVP*: ~{N}'-(2-fluorophenyl)-1,2-oxazole-5-carbohydrazide
Source	southampton virus (serotype 3) southampton virus (strain gi/human/united kingdom/southampton/1991)
Keywords	HYDROLASE / Viral protease.