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-Structure paper
Title | AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins. |
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Journal, issue, pages | J. Biol. Chem., Vol. 294, Page 13106-13116, Year 2019 |
Publish date | Mar 12, 2019 (structure data deposition date) |
![]() | Saline, M. / Badertscher, L. / Wolter, M. / Lau, R. / Gunnarsson, A. / Jacso, T. / Norris, T. / Ottmann, C. / Snijder, A. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.9 - 2.3 Å |
Structure data | ![]() PDB-6qzr: ![]() PDB-6qzs: |
Chemicals | ![]() ChemComp-B3P: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | PEPTIDE BINDING PROTEIN / protein binding / 14-3-3 / FOXO1 / complex |