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-Structure paper
Title | Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 117, Page 4109-4116, Year 2020 |
Publish date | Jun 25, 2019 (structure data deposition date) |
Authors | Cho, J. / Lee, M. / Cochrane, C.S. / Webster, C.G. / Fenton, B.A. / Zhao, J. / Hong, J. / Zhou, P. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:32041866 |
Methods | X-ray diffraction |
Resolution | 1.92 - 2.26 Å |
Structure data | PDB-6ph9: PDB-6pib: PDB-6pj3: |
Chemicals | ChemComp-MN: ChemComp-LP5: ChemComp-PG4: ChemComp-CA: ChemComp-EDO: ChemComp-HOH: ChemComp-OKV: ChemComp-OKY: |
Source |
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Keywords | BIOSYNTHETIC PROTEIN / lipid A / LpxH / lipid X / AZ1 / inhibitor / JH-LPH-33 |