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TitleNMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle.
Journal, issue, pagesNat Commun, Vol. 11, Page 1067-1067, Year 2020
Publish dateJun 11, 2019 (structure data deposition date)
AuthorsKosciuk, T. / Price, I.R. / Zhang, X. / Zhu, C. / Johnson, K.N. / Zhang, S. / Halaby, S.L. / Komaniecki, G.P. / Yang, M. / DeHart, C.J. ...Kosciuk, T. / Price, I.R. / Zhang, X. / Zhu, C. / Johnson, K.N. / Zhang, S. / Halaby, S.L. / Komaniecki, G.P. / Yang, M. / DeHart, C.J. / Thomas, P.M. / Kelleher, N.L. / Christopher Fromme, J. / Lin, H.
External linksNat Commun / PubMed:32103017
MethodsX-ray diffraction
Resolution1.93 - 2.52 Å
Structure data

PDB-6pau:
Structure of Human NMT2 with myristoyl-lysine peptide and CoA products
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

PDB-6pav:
Structure of Human NMT1 with products CoA and myristoyl-lysine peptide with acetylated N-terminus
Method: X-RAY DIFFRACTION / Resolution: 2.52 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-4PS:
4'-diphospho pantetheine

ChemComp-SO4:
SULFATE ION

ChemComp-MYR:
MYRISTIC ACID

ChemComp-HOH:
WATER

ChemComp-COA:
COENZYME A

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / lysine / myristoyl / myristoylation / n-myristoyl transferase

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