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Structure paper

TitleAn interbacterial toxin inhibits target cell growth by synthesizing (p)ppApp.
Journal, issue, pagesNature, Vol. 575, Page 674-678, Year 2019
Publish dateMay 3, 2019 (structure data deposition date)
AuthorsAhmad, S. / Wang, B. / Walker, M.D. / Tran, H.R. / Stogios, P.J. / Savchenko, A. / Grant, R.A. / McArthur, A.G. / Laub, M.T. / Whitney, J.C.
External linksNature / PubMed:31695193
MethodsX-ray diffraction
Resolution2.17 - 2.55 Å
Structure data

PDB-6ott:
Structure of PurF in complex with ppApp
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-6ox6:
Crystal structure of the complex between the Type VI effector Tas1 and its immunity protein
Method: X-RAY DIFFRACTION / Resolution: 2.17 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-N7Y:
adenosine 3',5'-bis(trihydrogen diphosphate)

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • escherichia coli (strain k12) (bacteria)
  • pseudomonas aeruginosa (bacteria)
Keywordscytosolic protein / transferase / complex with ppApp / type VI secretion / bacterial warfare / (p)ppApp / alarmone / Pseudomonas aeruginosa / Structural Genomics / Center for Structural Genomics of Infectious Diseases / CSGID

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