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-Structure paper
Title | Mechanism of Inactivation of Ornithine Aminotransferase by (1S,3S)-3-Amino-4-(hexafluoropropan-2-ylidenyl)cyclopentane-1-carboxylic Acid. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 141, Page 10711-10721, Year 2019 |
Publish date | Apr 9, 2019 (structure data deposition date) |
Authors | Moschitto, M.J. / Doubleday, P.F. / Catlin, D.S. / Kelleher, N.L. / Liu, D. / Silverman, R.B. |
External links | J. Am. Chem. Soc. / PubMed:31251613 |
Methods | X-ray diffraction |
Resolution | 1.777 Å |
Structure data | PDB-6oia: |
Chemicals | ChemComp-PLP: ChemComp-GOL: ChemComp-MQ4: ChemComp-HOH: |
Source |
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Keywords | TRANSFERASE / Human Ornithine Aminotransferase (hOAT) Mechanism Based Inhibitors Hepatocellular Carcinoma PLP |