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-Structure paper
Title | Structural basis for allosteric PARP-1 retention on DNA breaks. |
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Journal, issue, pages | Science, Vol. 368, Year 2020 |
Publish date | Jan 30, 2019 (structure data deposition date) |
![]() | Zandarashvili, L. / Langelier, M.F. / Velagapudi, U.K. / Hancock, M.A. / Steffen, J.D. / Billur, R. / Hannan, Z.M. / Wicks, A.J. / Krastev, D.B. / Pettitt, S.J. ...Zandarashvili, L. / Langelier, M.F. / Velagapudi, U.K. / Hancock, M.A. / Steffen, J.D. / Billur, R. / Hannan, Z.M. / Wicks, A.J. / Krastev, D.B. / Pettitt, S.J. / Lord, C.J. / Talele, T.T. / Pascal, J.M. / Black, B.E. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.8 - 2.9 Å |
Structure data | ![]() PDB-6ntu: ![]() PDB-6vkk: ![]() PDB-6vko: ![]() PDB-6vkq: |
Chemicals | ![]() ChemComp-DMS: ![]() ChemComp-1PE: ![]() ChemComp-L1S: ![]() ChemComp-SO4: ![]() ChemComp-HOH: ![]() ChemComp-RPB: ![]() ChemComp-GOL: ![]() ChemComp-UHB: |
Source |
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![]() | transferase/transferase inhibitor / PARP-1 / poly(ADP-ribose) polymerase / PARP inhibitor / PARP1 / ARTD1 / TRANSFERASE / transferase-transferase inhibitor complex / TRANSFERASE/INHIBITOR / TRANSFERASE-INHIBITOR complex |