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-Structure paper
Title | Targeting the ALS/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction. |
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Journal, issue, pages | Nucleic Acids Res., Vol. 49, Page 9526-9538, Year 2021 |
Publish date | Oct 31, 2019 (structure data deposition date) |
Authors | Jhan, C.R. / Satange, R. / Wang, S.C. / Zeng, J.Y. / Horng, Y.C. / Jin, P. / Neidle, S. / Hou, M.H. |
External links | Nucleic Acids Res. / PubMed:33836081 |
Methods | X-ray diffraction |
Resolution | 1.578 - 2.94 Å |
Structure data | PDB-6l75: PDB-6l76: PDB-7bpv: |
Chemicals | ChemComp-HOH: ChemComp-CPH: ChemComp-NI: ChemComp-SO4: |
Source |
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Keywords | DNA / A form DNA / GGGGCC motif / GC rich duplex / G4C2 / Duplex DNA / nucleotide flipping-out / Hoogsteen base pair / DNA-RNA HYBRID / G4C2 repeat / GGCC motif / A-like DNA structure |