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Structure paper

TitleMycobacterium tuberculosis CRISPR/Cas system Csm1 holds clues to the evolutionary relationship between DNA polymerase and cyclase activity.
Journal, issue, pagesInt. J. Biol. Macromol., Vol. 170, Page 140-149, Year 2020
Publish dateJun 24, 2019 (structure data deposition date)
AuthorsZhang, S. / Li, T. / Huo, Y. / Yang, J. / Fleming, J. / Shi, M. / Wang, Y. / Wei, W. / Gu, S. / Bi, L. ...Zhang, S. / Li, T. / Huo, Y. / Yang, J. / Fleming, J. / Shi, M. / Wang, Y. / Wei, W. / Gu, S. / Bi, L. / Jiang, T. / Zhang, H.
External linksInt. J. Biol. Macromol. / PubMed:33352158
MethodsX-ray diffraction
Resolution2.295 - 3 Å
Structure data

PDB-6kbd:
fused To-MtbCsm1 with 2dATP
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-6kc0:
fused To-MtbCsm1 with 2ATP
Method: X-RAY DIFFRACTION / Resolution: 2.295 Å

Chemicals

ChemComp-DTP:
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • thermococcus onnurineus na1 (archaea)
  • mycobacterium tuberculosis h37rv (bacteria)
KeywordsDNA BINDING PROTEIN / Csm1 / polymersase

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